Ulcerative Colitis Clinical Trials - Enhancing Care and the Future of Treatment

Dive into the world of Ulcerative Colitis Clinical Trials with FOMAT Medical Research. Our focus is on improving treatment possibilities for Ulcerative Colitis by conducting detailed clinical trials. We aim to assist individuals looking for new treatment options and entities seeking collaboration in clinical research.

Colorectal cancer treatment

What is Ulcerative Colitis?

Ulcerative Colitis (UC) is a chronic condition characterized by inflammation and the formation of ulcers in the colon and rectum. It's classified as an inflammatory bowel disease (IBD), a category that also includes Crohn's disease. UC affects the innermost lining of the large intestine and rectum, causing swelling, redness, and sores or ulcers. The progression of UC can vary greatly among individuals—some may experience mild symptoms, while others may face severe, life-disrupting complications.

Understanding Ulcerative Colitis

Symptoms of Ulcerative Colitis

  • Abdominal pain and cramping due to the inflammation and ulcers in the colon.
  • Frequent and urgent bowel movements, a result of irritation in the colon and rectum.
  • Blood in the stool, which may appear as bright red or dark, indicating bleeding in the colon.
  • Fatigue, often a consequence of the body’s resources being used to fight inflammation and due to possible blood loss.
  • Weight loss and reduced appetite, which can occur as eating may trigger discomfort or pain.

Causes and Risk Factors of Ulcerative Colitis

Overview of Potential Causes

While the exact cause of ulcerative colitis is unknown, it's thought to result from an abnormal response of the immune system to gut bacteria.

Genetic Predisposition

Family history increases the risk, suggesting genetics play a significant role in susceptibility to the disease.

Environmental Factors and Immune System

Diet, pollution, and stress, among others, can trigger or exacerbate symptoms, highlighting the complex interplay between environment and immunity.

Lifestyle Factors

Smoking, diet, and physical activity levels can influence the course of the disease, pointing to lifestyle adjustments as part of comprehensive care.

Complications of Ulcerative Colitis: Understanding Clinical Issues Involved

Importance of Early Detection

Prompt diagnosis and management are critical to prevent severe complications and improve quality of life for those affected.

Short-Term Complications During Active Disease

  • Dehydration and Malnutrition: Due to loss of fluids and nutrients.
  • Severe Bleeding and Anemia: Resulting from ulceration.
  • Toxic Megacolon: A rare but life-threatening enlargement of the colon.

Long-Term Complications and Risks

  • Colorectal Cancer: A significantly increased risk among patients.
  • Osteoporosis: Due to malabsorption of calcium and vitamin D.
  • Liver and Kidney Problems: Resulting from chronic inflammation and medication side effects.

What are Clinical Trials?

Clinical trials are research studies performed in people that aim to evaluate a medical, surgical, or behavioral intervention. They are the primary way researchers discover whether new treatments, like drugs, diets, or medical devices, are safe and effective in humans. Specifically, in the realm of Ulcerative Colitis, clinical trials explore new ways to treat, diagnose, and understand the disease. Participating in a clinical trial offers the chance to contribute to medical research and possibly gain access to the latest treatments before they're widely available.

Why Participate in Clinical Trials?

Participating in clinical trials offers several benefits. For one, you gain access to new treatments for Ulcerative Colitis that are not yet available to the public. This could potentially lead to personal health improvements when standard treatments have failed. Additionally, participants contribute valuable information that helps researchers better understand Ulcerative Colitis, leading to advancements in the disease's management and care. By joining a clinical trial, you play a part in the development of new medical interventions that can improve the lives of future patients. Moreover, clinical trials often provide participants with close monitoring by healthcare professionals, offering an added layer of care.

Our Active Studies

We have several clinical trials focused on ulcerative colitis. By participating, you can access new treatments and help advance medical research. To learn more about our current studies and see if you are eligible, please visit our dedicated page with all active ulcerative colitis trials.

  • Camarillo, Oxnard

    Ulcerative Colitis

    Ulcerative Colitis, a form of Inflammatory Bowel Disease (IBD), leads to inflammation, ulcers, and stomach discomfort. We are currently running a clinical study to test the effectiveness and safety of a new Alfa Induction Therapy for individuals suffering from Ulcerative Colitis.

    Criteria & Qualifications: • Must be 18 years old or above.
    • Recently diagnosed with Ulcerative Colitis within the past 3 months.
    • Agreeable to submit medical history documentation.

    Compensation: Contact us for more information

    Read more
  • Arcadia, Glendora, Monrovia, Oxnard, Pasadena

    Ulcerative Colitis Study

    Ulcerative Colitis causes inflammation and ulcers in the colon, resulting in abdominal discomfort. This study evaluates a new treatment's efficacy and safety for those with moderate to severe conditions. It targets individuals unsatisfied with or affected by current therapies' side effects.

    Criteria & Qualifications: • Is at least 18 years of age or older.
    • Diagnosed with Ulcerative Colitis.
    • Is willing to provide medical records.

    Compensation: Contact Us For More information

    Read more
  • Santa Maria

    Ulcerative Colitis Study

    Ulcerative Colitis is a type of IBD that causes inflammation, sores, and abdominal pain. This clinical trial is being conducted to evaluate the safety and efficacy of an investigational Alfa Induction Therapy in people with Ulcerative Colitis.

    Criteria & Qualifications: • Is at least 16 years of age or older.
    • Is willing to provide medical records.

    Compensation: Contact us for more information

    Read more

Frequently Asked Questions

The length of a clinical trial varies depending on several factors, such as the type of illness and the type of medicine being researched. For example, if the study is researching a treatment for a chronic condition, participants’ progress on the trial may be tracked over a relatively long period of time. Studies of antibiotics on the other-hand conclude quickly as patients are typically treated on study for a few days only.


Depending on the study and the study process, in some cases, you will have to keep track of your process, in other cases you will not, but you will have the support and guidance of the research team.

As a research participant, you have the right to drop out of a study at anytime, the right to be given new information about the study, and the right to ask questions at anytime and have them answered promptly.

Yes. Although the purpose of the study is not to treat an individual for any health condition, a study may involve clinical procedures such as an MRI, blood tests, hearing tests, etc. In order to complete these and other tests, the researcher must know the volunteer's general state of health to ensure his or her safety during the clinical study process.


No, you do not have to be a US citizen to participate in a clinical trial. We also do not ask for your social security number. All we ask is that you have a physical address and some form of ID that we can use during the enrollment process.

Sure, you can refer any friend or family member who is willing to participate in a study, for more information click here!

Who is FOMAT Medical Research?

FOMAT Medical Research is California's largest research site network, dedicated to advancing clinical research and improving patient outcomes. With an extensive network of research sites and a relentless commitment to innovating healthcare through diversity, FOMAT Medical Research collaborates with industry Sponsors and CROs to accelerate the development of groundbreaking therapies across multiple therapeutic areas. FOMAT is a founding member of hyperCORE International, a super network of fully professionalized research site organizations.

FOMAT has a strong focus on ulcerative colitis, having conducted over 25 trials in this area and more than 100 GI studies. We collaborate with over 15 expert gastroenterologists and Principal Investigators in the region to bring innovative treatments to patients.

Let's Partner to Accelerate Ulcerative Colitis Research

At FOMAT Medical Research, we are dedicated to advancing the understanding and treatment of ulcerative colitis. Our extensive experience in conducting clinical trials and our commitment to diversity in research make us a leader in this crucial field.

FOMAT's Involvement in Ulcerative Colitis Research

  • Experience and Expertise: With a proven track record of successful clinical trials, FOMAT has been at the forefront of ulcerative colitis research. Our team of experts and state-of-the-art facilities ensure the highest standards in clinical research.

  • Commitment to Diversity: We believe that diversity in clinical trials leads to better health outcomes for all. Our research sites are located in diverse communities, allowing us to engage a broad spectrum of participants and ensure our findings are inclusive and applicable to everyone.

  • Collaborative Approach: We work closely with sponsors, healthcare professionals, and patients to create a collaborative environment that fosters innovation and accelerates the development of new treatments.

Meet Our Experts

FOMAT supports ulcerative colitis clinical trials by providing valuable resources and collaboration opportunities with experienced physicians. Our network includes over 20 expert gastroenterologists with extensive experience in ulcerative colitis research.


Karen Simon, MD

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Camarillo & Oxnard, CA

Elias A. Tarakji, MD

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Arcadia, CA

Dr. Keval Shah, DO

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Santa Maria, CA