In experiments with human colon cancer cells and mice, a team led by scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer origins when a normal part of cells’ machinery generally used to repair DNA damage is diverte ...
Immunologists at St. Jude Children's Research Hospital have discovered that a protein called NLRC3 plays a central role in inhibiting colon cells from becoming cancerous. The study, led by Thirumala-Devi Kanneganti, Ph.D., a mem ...
A distinct pattern in the changing length of blood telomeres, the protective end caps on our DNA strands, can predict cancer many years before actual diagnosis, according to a new study from Northwestern Medicine in collaboration with Harvard Univers ...
When prostate cancer advances to the point of spreading, the larger and more stubborn tumors develop cells that suppress the body’s immune response – and defeat doctors’ attempts to launch an attack on it, experts said. But through chemoimmunotherap ...
Get today's drug discovery & development headlines and news - Sign up now! Taking aspirin reduces a person’s risk of colorectal cancer, but the molecular mechanisms involved have remained unknown until a recent discovery by The Hormel Institute, ...
For the first time, it has been shown that many mutations in tumors--20 percent—are immunogenic, or able to rouse armies of T cells, post-vaccine. Also for the first time, it has been shown that most of those roused T cell armies are helper CD4+ T ce ...
Pancreatic cancer could be diagnosed up to two years earlier by screening for two tumor markers found in blood, according to research published in Clinical Cancer Research. The study, conducted by researchers from UCL, UCL Hospital Foundation Trust ...
The drugs were designed to keep cancer cells at bay by preventing their growth, survival and spread. Yet, after clinical trials, they left scientists scratching their heads and drug developers watching their investments succumb to cancer’s latest tri ...
Nanoparticle drugs—tiny containers packed with medicine and with the potential to be shipped straight to tumors—were thought to be a possible silver bullet against cancer. However new cancer drugs based on nanoparticles have not improved overall surv ...
At the Virginia Tech Carilion Research Institute, three scientists are planning to create a virus capable of destroying brain cancer. It sounds like the stuff of science fiction, but it isn’t hypothetical – the researchers were recently awarded a gra ...