Effects of the medicine may alter by the Distinct Human Mutations. Every person has a unique DNA sequence. In a new study published in the scientific journal Cell, they look at certain receptors (GPCRs) in human cells. These protein receptors are the main targets of the biggest group of marketed modern medicine.
By mining existing data sets, they have mapped the extent to which mutations occur within GPCR drug targets in individuals and studied what impact these mutations could have on the therapeutic effect of medicine.